arp3 polyclonal antibody (Proteintech)
Structured Review

Arp3 Polyclonal Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/arp3 polyclonal antibody/product/Proteintech
Average 94 stars, based on 2 article reviews
Images
1) Product Images from "AVIL promotes osteosarcoma progression and cisplatin resistance via ARP2/3-mediated DNA damage repair"
Article Title: AVIL promotes osteosarcoma progression and cisplatin resistance via ARP2/3-mediated DNA damage repair
Journal: Translational Oncology
doi: 10.1016/j.tranon.2025.102654
Figure Legend Snippet: AVIL interacts with the ARP2/3 Complex and is associated with DNA damage repair pathways in osteosarcoma cells. (A) The volcano plot of RNA-seq on 143b cells treated with OE CTRL or OE AVIL . (B) GO analysis of the biological process pathways. (C) GSEA of the “GO CC DNA repair complex”. (D) Co-IP shows the interaction among AVIL and ARP3. (E-H) RT-qPCR results for relative expression of BRCA1(E), BRCA2 (F), XRCC4 (G), ATM (H).
Techniques Used: RNA Sequencing, Co-Immunoprecipitation Assay, Quantitative RT-PCR, Expressing
Figure Legend Snippet: AVIL promotes osteosarcoma progression and cisplatin resistance through interaction with the ARP2/3 complex. (A) The wound-healing assay (scale bar: 100 μm). (B) Quantification of wound-healing assay. (C) The half maximal inhibitory concentration (IC50) of cisplatin of 143b cells. (D) The comet assay indicates DNA damage (scale bar: 50 μm). (E) Analysis of phosphorylated H2A histone family member X (γ-H2AX) with 5 μM cisplatin (scale bar: 200 μm). (F) Ratio of γ-H2AX positive cell.
Techniques Used: Wound Healing Assay, Concentration Assay, Single Cell Gel Electrophoresis